Drugs
Read-only from the Statory library · approved cards only · no estimates · exported 2026-11-04
224 cards · 44 from Korea · newest year first
(Korean title)
(Korean authors) · 2026 · South Korea
(Korean)
- Country
- South Korea
- Design
- Other
- Licence
- Other
(Korean title)
(Korean authors) · 2026 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 15,842
- Design
- Meta-analysis
- Licence
- Other
(Korean title)
(Korean authors) · 2026 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 22
- Design
- Qualitative
- Licence
- Other
(Korean title)
(Korean authors) · 2026 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 42
- Design
- Cross-sectional
- Licence
- Other
(Korean title)
(Korean authors) · 2026 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 154
- Design
- Cross-sectional
- Licence
- Other
(Korean title)
(Korean authors) · 2026 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 198
- Design
- Cross-sectional
- Licence
- Other
Follow-Up Patterns at a Low-Threshold Mobile Medical Unit Providing Opioid Use Disorder Care in an Urban Setting: A Group-Based Trajectory Modeling Approach
Shah et al. · 2026 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 964
- Design
- Other
- Licence
- CC BY
"This whole thing is relationship medicine": A qualitative analysis of mobile and street-delivered medication for opioid use disorder in King County, Washington, using RE-AIM
Strong et al. · 2026 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 21
- Design
- Qualitative
- Licence
- CC BY
Cannabinoid CB1 receptor and mu-opioid receptor interaction: new insights from conditional knockout mice
Alton et al. · 2026 · Country not stated
CB1R and MOR mRNAs showed distinct regional distributions in mouse brain, with colocalization primarily in the paraventricular nucleus of the thalamus. In the PVT, ~50% of Vglut2-positive glutamatergic neurons displayed CB1R-MOR co-expression. Only 5%–25% of Vglut2-positive neurons in PAG and spinal dorsal horn, or Vgat-positive GABA neurons in NAc, VTA, and substantia nigra, showed colocalization. Selective MOR deletion from Vglut2+ or Vgat+ neurons did not alter Δ9-THC-induced analgesia, hypothermia, catalepsy, rotarod impairment, or conditioned place aversion. CB1R deletion from GABAergic neurons did not affect oxycodone-induced analgesia, hypothermia, or conditioned place preference.
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
Effects of Alpha-Band Binaural Beat Entrainment on Anxiety and Aggression in Men With Opioid Use Disorder: A Randomized Sham-Controlled Trial
Soleimanifar et al. · 2026 · Iran
(Korean)
- Country
- Iran
- Sample
- n = 30
- Design
- Other
- Licence
- CC BY
Clinical Profile and Risk Factors of Deliberate Self-Harm Among Patients Presenting to a Tertiary Care Hospital in Bangladesh
Bhuiyan et al. · 2026 · Bangladesh
Pesticide poisoning (39.2%) and drug overdose (31.7%) were the most common methods of deliberate self-harm. Vomiting (59.2%) and altered consciousness (28.3%) were the most frequent clinical features; 19.2% required ICU admission. Psychosocial stressors were present in 74.2%, psychiatric illness in 35.0%, and substance use in 30.0% of patients. Previous DSH was associated with psychiatric illness (68.0% vs 26.3%, p=0.001) and psychosocial factors (96.0% vs 68.4%, p=0.003). Substance use was associated with previous DSH (52.0% vs 24.2%, p=0.014); sex was not (p=0.118).
- Country
- Bangladesh
- Sample
- n = 120
- Design
- Cross-sectional
- Licence
- CC BY
Buprenorphine initiation by a street medicine program is associated with reduced opioid-related emergency department utilization among people experiencing homelessness
Wallace et al. · 2026 · United States
(Korean)
- Country
- United States
- Sample
- n = 115
- Design
- Other
- Licence
- Other
Navigating pregnancy and addiction recovery: Patient perspectives on perinatal care interventions for women with opioid use disorder in Kentucky, USA
Surratt et al. · 2026 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 33
- Design
- Qualitative
- Licence
- Other
Treatment of opioid use disorder in pregnancy among individuals with and without co-occurring stimulant use disorder: A retrospective cohort study
Charron et al. · 2026 · United States
(Korean)
- Country
- United States
- Sample
- n = 1,206
- Design
- Other
- Licence
- Other
(Korean title)
(Korean authors) · 2026 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 7
- Design
- Qualitative
- Licence
- Other
Fentanyl Education and Harm Reduction Developmental Program for Churches and Agencies in Norfolk, Virginia
Miller · 2026 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Other
- Licence
- Other
Economic analysis of a low-threshold mobile medical unit dispensing buprenorphine for opioid use disorder
Shah et al. · 2026 · United States
(Korean)
- Country
- United States
- Sample
- n = 30
- Design
- Cross-sectional
- Licence
- Other
A qualitative study investigating the role of humor in supporting recovery from addiction
Stull et al. · 2026 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 11
- Design
- Qualitative
- Licence
- Other
(Korean title)
(Korean authors) · 2025 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 22
- Design
- Qualitative
- Licence
- Other
(Korean title)
(Korean authors) · 2025 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 1,020
- Design
- Other
- Licence
- Other
(Korean title)
(Korean authors) · 2025 · South Korea
Also covers · Tobacco
(Korean)
- Country
- South Korea
- Sample
- n = 1,477
- Design
- Other
- Licence
- Other
(Korean title)
(Korean authors) · 2025 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 4
- Design
- Qualitative
- Licence
- Other
(Korean title)
(Korean authors) · 2025 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 4
- Design
- Qualitative
- Licence
- Other
(Korean title)
(Korean authors) · 2025 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 3
- Design
- Qualitative
- Licence
- Other
(Korean title)
(Korean authors) · 2025 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 9
- Design
- Qualitative
- Licence
- Other
(Korean title)
(Korean authors) · 2025 · South Korea
(Korean)
- Country
- South Korea
- Design
- Qualitative
- Licence
- Other
Addressing the legal and health challenges of licensed medical cannabis users who want to travel abroad
Bonny-Noach et al. · 2025 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 15
- Design
- Qualitative
- Licence
- CC BY
(Korean title)
(Korean authors) · 2025 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 3
- Design
- Qualitative
- Licence
- Other
(Korean title)
(Korean authors) · 2025 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 3
- Design
- Qualitative
- Licence
- Other
(Korean title)
(Korean authors) · 2025 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 19
- Design
- Qualitative
- Licence
- Other
(Korean title)
(Korean authors) · 2025 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 669
- Design
- Other
- Licence
- Other
(Korean title)
(Korean authors) · 2025 · South Korea
(Korean)
- Country
- South Korea
- Design
- Other
- Licence
- Other
(Korean title)
(Korean authors) · 2025 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 10
- Design
- Qualitative
- Licence
- Other
(Korean title)
(Korean authors) · 2025 · Canada
(Korean)
- Country
- Canada
- Sample
- n = 3,406
- Design
- Other
- Licence
- Other
(Korean title)
(Korean authors) · 2025 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 50
- Design
- Other
- Licence
- Other
The role of depression in the relationship between cannabis use and suicidal behaviours: A systematic review and meta-analysis
Maviel et al. · 2025 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Meta-analysis
- Licence
- CC BY
(Korean title)
(Korean authors) · 2025 · South Korea
(Korean)
- Country
- South Korea
- Design
- Cross-sectional
- Licence
- Other
(Korean title)
(Korean authors) · 2025 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 3
- Design
- Qualitative
- Licence
- Other
(Korean title)
(Korean authors) · 2025 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 10
- Design
- Qualitative
- Licence
- Other
(Korean title)
(Korean authors) · 2025 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 9
- Design
- Qualitative
- Licence
- Other
(Korean title)
(Korean authors) · 2025 · South Korea
(Korean)
- Country
- South Korea
- Design
- Qualitative
- Licence
- Other
(Korean title)
(Korean authors) · 2024 · South Korea
(Korean)
- Country
- South Korea
- Design
- Other
- Licence
- Other
(Korean title)
(Korean authors) · 2024 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 42
- Design
- Cross-sectional
- Licence
- Other
(Korean title)
(Korean authors) · 2024 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 30
- Design
- Other
- Licence
- Other
(Korean title)
(Korean authors) · 2024 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 19
- Design
- Cross-sectional
- Licence
- Other
(Korean title)
(Korean authors) · 2024 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 3
- Design
- Qualitative
- Licence
- Other
Contextualizing medications for opioid use disorder and peer support service provision in the probation system with implementation science
Kang et al. · 2024 · United States
(Korean)
- Country
- United States
- Sample
- n = 10
- Design
- Qualitative
- Licence
- CC BY
Referral to and engagement in substance use disorder treatment within opioid intervention courts in New York: a qualitative study of implementation barriers and facilitators
O’Grady et al. · 2024 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 46
- Design
- Qualitative
- Licence
- CC BY
The relationship between felt stigma and non-fatal overdose among rural people who use drugs
Sibley et al. · 2024 · United States
(Korean)
- Country
- United States
- Sample
- n = 2,608
- Design
- Cross-sectional
- Licence
- CC BY
Reviewing the Impact of Maternal Opioid Use Disorder on Fetal Development and Long-Term Pediatric Health Outcomes
Asad et al. · 2024 · United States
(Korean)
- Country
- United States
- Design
- Other
- Licence
- CC BY
Using alone at home: What's missing in housing-based responses to the overdose crisis?
Fleming et al. · 2024 · United States
(Korean)
- Country
- United States
- Design
- Other
- Licence
- CC BY
Stalled Scale-Up of Opioid Agonist Therapies for HIV Prevention in Kazakhstan: History, Policy, and Recommendations for Change
Liberman et al. · 2024 · Kazakhstan
(Korean)
- Country
- Kazakhstan
- Sample
- n = 95,000
- Design
- Other
- Licence
- CC BY
Fact vs. fiction: naloxone in the treatment of opioid-induced respiratory depression in the current era of synthetic opioids
Dahan et al. · 2024 · United States
(Korean)
- Country
- United States
- Sample
- n = 1,000,000
- Design
- Other
- Licence
- CC BY
(Korean title)
(Korean authors) · 2024 · South Korea
(Korean)
- Country
- South Korea
- Design
- Qualitative
- Licence
- Other
(Korean title)
(Korean authors) · 2024 · South Korea
Also covers · Gaming
(Korean)
- Country
- South Korea
- Sample
- n = 96
- Design
- Other
- Licence
- Other
A systematic review and meta-analysis of neuromodulation therapies for substance use disorders
Mehta et al. · 2024 · Country not stated
rTMS reduced substance use and craving with medium to large effect sizes (Hedge's g > 0.5). Multiple stimulation sessions and left DLPFC targeting were most encouraging for rTMS. tDCS produced medium effect sizes for drug use and craving, though highly variable and less robust than rTMS. Right anodal DLPFC stimulation appeared most efficacious for tDCS. DBS studies were typically small and uncontrolled but showed promise in reducing misuse of multiple substances.
- Country
- Country not stated
- Design
- Meta-analysis
- Licence
- CC BY
The Implementation of Drug Abuse Rehabilitation to Prevent Relapse: A Systematic Literature Review
Erliyani et al. · 2024 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 27
- Design
- Meta-analysis
- Licence
- Other
Intersectionality and Structural Drivers of Fatal Overdose Disparities in the United States: a Narrative Review
Valasek et al. · 2023 · United States
(Korean)
- Country
- United States
- Design
- Qualitative
- Licence
- CC BY
Impacts of recreational cannabis legalization on use and harms: A narrative review of sex/gender differences
Matheson et al. · 2023 · Ireland
Men have always been more likely to use cannabis than women, yet the sex/gender gap in prevalence has narrowed over time, possibly partly due to legalization. Women had lower odds (OR = 0.66) of favorable attitudes toward cannabis acceptability than men in 1,713 Canadian undergraduates. In 507 Irish adolescents, boys were more likely than girls to perceive cannabis as safe (OR = 2.02). Female gender was associated with lower odds of supporting cannabis legalization (OR = 0.46) in a Michigan survey of 2,190 adults. Evidence on sex/gender differences in legalization impacts on harms such as motor vehicle collisions and hospitalizations is more variable.
- Country
- Ireland
- Sample
- n = 2,190
- Design
- Other
- Licence
- CC BY
Qualitative exploration of the early experiences of opioid use disorder patients from private clinics after Russia's invasion of Ukraine in five major cities in Ukraine
Mazhnaya et al. · 2023 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 20
- Design
- Qualitative
- Licence
- CC BY
Signaling-specific inhibition of the CB1 receptor for cannabis use disorder: phase 1 and phase 2a randomized trials
(Korean authors) · 2023 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 40
- Design
- Other
- Licence
- CC BY
Effects of cannabidiol on anandamide levels in individuals with cannabis use disorder: findings from a randomised clinical trial for the treatment of cannabis use disorder
Hua et al. · 2023 · United Kingdom
(Korean)
- Country
- United Kingdom
- Sample
- n = 70
- Design
- Other
- Licence
- CC BY
Prescribed and Penalized: The Detrimental Impact of Mandated Reporting for Prenatal Utilization of Medication for Opioid Use Disorder
Work et al. · 2023 · United States
(Korean)
- Country
- United States
- Sample
- n = 26
- Design
- Qualitative
- Licence
- CC BY
“I’m not going to lay back and watch somebody die”: a qualitative study of how people who use drugs’ naloxone experiences are shaped by rural risk environment and overdose education/naloxone distribution intervention
Kesich et al. · 2023 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 29
- Design
- Qualitative
- Licence
- CC BY
“As safe as possible”: a qualitative study of opioid withdrawal and risk behavior among people who use illegal opioids
Frank et al. · 2023 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 32
- Design
- Qualitative
- Licence
- CC BY
Biopsychosocial contexts of timely and adequate prenatal care utilization among women with criminal legal involvement and opioid use disorder
Satcher et al. · 2023 · United States
(Korean)
- Country
- United States
- Sample
- n = 317
- Design
- Cross-sectional
- Licence
- CC BY
Health care and harm reduction provider perspectives on treating older adults who use non-medical opioids: a qualitative study set in Chicago
Mason et al. · 2023 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 26
- Design
- Qualitative
- Licence
- CC BY
Tailoring dissemination strategies to increase evidence-informed policymaking for opioid use disorder treatment: study protocol
Crable et al. · 2023 · Country not stated
Only 48.2% of adult Medicaid members and 4.7% of CHIP members living with opioid use disorder receive any evidence-based medications for opioid use disorder (MOUD). 18 state Medicaid agencies require prior authorizations for injectable naltrexone, while 39 agencies require prior authorization for oral buprenorphine. Nearly 36% of MCOs surveyed require prior authorization for MOUD, with MCOs differentially imposing these policies on access to buprenorphine, methadone, and naltrexone. Nearly 70% of all Medicaid members across the USA are enrolled in MCOs. Medicaid and CHIP provide health insurance benefits including 38% of individuals in the USA living with an opioid use disorder.
- Country
- Country not stated
- Design
- Cross-sectional
- Licence
- CC BY
Opioid, methamphetamine, and polysubstance use: perinatal outcomes for the mother and infant
Wouldes et al. · 2023 · United States
(Korean)
- Country
- United States
- Sample
- n = 21,905
- Design
- Other
- Licence
- CC BY
Responding to health policy recommendations on managing opioid use disorder during Russia's invasion of Ukraine: Divergent responses from the frontline to the west
Ivasiy et al. · 2023 · Ukraine
(Korean)
- Country
- Ukraine
- Sample
- n = 8
- Design
- Qualitative
- Licence
- CC BY
Cannabis sativa: Applications of Artificial Intelligence (AI) and Plant Tissue Culture for Micropropagation
Malabadi et al. · 2023 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Other
- Licence
- Other
Reducing the harms of xylazine: clinical approaches, research deficits, and public health context
Zagorski et al. · 2023 · United States
(Korean)
- Country
- United States
- Design
- Other
- Licence
- CC BY
Heroin assisted treatment for key health outcomes in people with chronic heroin addictions: A context-focused systematic review
McNair et al. · 2023 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 2,331
- Design
- Meta-analysis
- Licence
- CC BY
(Korean title)
(Korean authors) · 2023 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 4
- Design
- Qualitative
- Licence
- Other
Barriers and facilitators to the use of medication for opioid use disorder within the criminal justice system: Perspectives from clinicians
Booty et al. · 2023 · United States
(Korean)
- Country
- United States
- Sample
- n = 25
- Design
- Qualitative
- Licence
- Other
The endocannabinoid system as a putative target for the development of novel drugs for the treatment of psychiatric illnesses
Hill et al. · 2023 · Country not stated
Cannabis is well established to impact affective states, emotion and perceptual processing, primarily through its interactions with the endocannabinoid system. Approximately 19% of individuals who use cannabis develop a cannabis use disorder (CUD). The few studies that have looked at therapeutic effect of cannabis itself have not found robust outcomes associated with cannabis. Inhibitors of endocannabinoid metabolism or modulators of cannabinoid receptor signaling have emerged as potential candidates for the treatment of psychiatric conditions. The current data available is quite promising and shows indications of several potential candidate diseases which may benefit from this approach.
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
δ-opioid Receptor, Microglia and Neuroinflammation
Xu et al. · 2023 · Country not stated
Microglia are the major effector of neuroinflammation and account for 10% of total cerebral cells. DOR activation or overexpression protects neurons against hypoxic/ischemic and neurodegenerative injury via MAPKs, Nrf2 and PI3K/Akt pathways. DOR activation strongly protected neurons from hypoxia- and LPS-induced injury by inhibiting microglial pro-inflammatory transformation. Knocking-down DOR or restraining DOR activity promoted microglia activation and inflammatory events with aggravation of cell injury. Activated microglia can induce the A1 phenotype of astrocytes through secreting IL-1α, TNF-α, and C1q, further damaging neurons.
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
(Korean title)
(Korean authors) · 2023 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 9
- Design
- Qualitative
- Licence
- Other
Pandemic telehealth flexibilities for buprenorphine treatment: A synthesis of evidence and policy implications for expanding opioid use disorder care in the U.S.
Krawczyk et al. · 2023 · United States
(Korean)
- Country
- United States
- Sample
- n = 41
- Design
- Meta-analysis
- Licence
- Quote only
Heroin and its metabolites: relevance to heroin use disorder
Milella et al. · 2023 · United States
(Korean)
- Country
- United States
- Design
- Other
- Licence
- CC BY
The role of neuroinflammation in the transition of acute to chronic pain and the opioid-induced hyperalgesia and tolerance
Echeverria-Villalobos et al. · 2023 · Country not stated
Activation of glial and immune cells increases production of proinflammatory mediators, creating a neuroinflammatory state. Neuroinflammation is a fundamental mechanism in the genesis of acute pain and its transition to neuropathic and chronic pain. Central sensitization, driven by microglial cytokines and chemokines, is crucial for chronification of acute pain. Activated immune and glial cells can disrupt opioid analgesic effects, contributing to tolerance, dependence, and paradoxical hyperalgesia. The incidence of pain persisting beyond wound healing after surgery is approximately 10%–85%, depending on the type of surgery.
- Country
- Country not stated
- Design
- Meta-analysis
- Licence
- CC BY
Xylazine in the Opioid Epidemic: A Systematic Review of Case Reports and Clinical Implications
Ayub et al. · 2023 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 59
- Design
- Meta-analysis
- Licence
- CC BY
Non-opioid analgesics for the prevention of chronic postsurgical pain: a systematic review and network meta-analysis
Doleman et al. · 2023 · Country not stated
i.v. lidocaine (OR 0.32; 95% CrI 0.17–0.58) reduced the incidence of chronic postsurgical pain at ≤6 months. Ketamine (OR 0.64; 95% CrI 0.44–0.92) reduced the incidence of chronic postsurgical pain at ≤6 months. Gabapentinoids (OR 0.67; 95% CrI 0.47–0.92) reduced the incidence of chronic postsurgical pain at ≤6 months. Dexmedetomidine (OR 0.36; 95% CrI 0.12–1.00) possibly reduced the incidence of chronic postsurgical pain at ≤6 months. Little available evidence existed for chronic postsurgical pain at >6 months, combinations of agents, chronic opioid use, and serious adverse events.
- Country
- Country not stated
- Sample
- n = 23,902
- Design
- Meta-analysis
- Licence
- CC BY
Preliminary analysis of self-reported quality health indicators of patients on opioid agonist therapy at specialty and primary care clinics in Ukraine: A randomized control trial
Pashchenko et al. · 2022 · Ukraine
(Korean)
- Country
- Ukraine
- Sample
- n = 818
- Design
- Other
- Licence
- CC BY
Beliefs and misperceptions about naloxone and overdose among U.S. laypersons: a cross-sectional study
Agley et al. · 2022 · United States
(Korean)
- Country
- United States
- Sample
- n = 702
- Design
- Cross-sectional
- Licence
- CC BY
Availability of medical cannabis services by racial, social, and geographic characteristics of neighborhoods in New York: a cross-sectional study
Cunningham et al. · 2022 · United States
(Korean)
- Country
- United States
- Sample
- n = 4,858
- Design
- Cross-sectional
- Licence
- CC BY
A measurement invariance analysis of selected Opioid Overdose Knowledge Scale (OOKS) items among bystanders and first responders
Swartz et al. · 2022 · United States
(Korean)
- Country
- United States
- Sample
- n = 1,795
- Design
- Cross-sectional
- Licence
- CC BY
Methamphetamine Exposure in Adolescent Impairs Memory of Mice in Adulthood Accompanied by Changes in Neuroplasticity in the Dorsal Hippocampus
Liang et al. · 2022 · China
(Korean)
- Country
- China
- Sample
- n = 72
- Design
- Other
- Licence
- CC BY
Assessing the feasibility, acceptability and accessibility of a peer-delivered intervention to reduce harm and improve the well-being of people who experience homelessness with problem substance use: the SHARPS study
Parkes et al. · 2022 · United Kingdom
(Korean)
- Country
- United Kingdom
- Sample
- n = 68
- Design
- Other
- Licence
- CC BY
Trend Analysis of Substance Use Disorder During Pregnancy
Ndanga et al. · 2022 · United States
(Korean)
- Country
- United States
- Sample
- n = 332,275
- Design
- Cross-sectional
- Licence
- CC BY
Delivering transcutaneous auricular neurostimulation (tAN) to improve symptoms associated with opioid withdrawal: results from a prospective clinical trial
Tirado et al. · 2022 · United States
(Korean)
- Country
- United States
- Sample
- n = 31
- Design
- Other
- Licence
- CC BY
Development of Goal Management Training+ for Methamphetamine Use Disorder Through Collaborative Design
Anderson et al. · 2022 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Qualitative
- Licence
- CC BY
The immediate and long-term effects of prenatal opioid exposure
Yen et al. · 2022 · Country not stated
Between 1999 and 2014, pregnant women with opioid use disorder increased from 1.5 to 6.5 cases per 1,000 hospital births, and NAS rose from 1.2 to 8.0 per 1,000 hospital births. Infants co-exposed to opioids and gabapentin had the highest absolute risk for severe NAS requiring pharmacologic treatment. Use of psychotropic medications in addition to prescription opioids increased NAS severity two-fold compared to prescription opioids alone. Infants randomized to 24 kcal/oz formula had greater weight gain than those receiving standard 20 kcal/oz formula. Punctate white matter lesions were reported in the brain of 8 of 20 opioid-exposed neonates.
- Country
- Country not stated
- Sample
- n = 20
- Design
- Other
- Licence
- CC BY
Endogenous opioid systems alterations in pain and opioid use disorder
Higginbotham et al. · 2022 · United States
Endogenous opioid systems comprise four receptor families (MOPR, KOPR, DOPR, NOPR) acting through β-endorphins, dynorphins, enkephalins, and nociceptins to maintain homeostasis. Over half of US adults reported pain symptoms within the past 3 months (Lucas et al., 2021). Provisional estimates of opioid overdose deaths exceeded 80,000 in 2021 (Ahmad et al., 2022). Metanalyses suggest rates of problematic prescription opioid use may occur in >80% of pain patients. Among those who misused prescription opioids, the most common reason for misuse was to relieve physical pain (65%).
- Country
- United States
- Design
- Other
- Licence
- CC BY
Current Status of Evidence for a New Diagnosis: Food Addiction-A Literature Review
Vasiliu · 2022 · Country not stated
A high prevalence of food addiction was found in the general population, up to 20% according to a meta-analytic research. The YFAS was constructed to match DSM IV criteria for substance dependence and validated for quantifying eating addiction severity. Reward dysfunction, impulsivity and emotion dysregulation have been considered basic mechanisms that trigger both eating dysfunctions and addictive behaviors. Genetic factors may be involved in this dependence, as modulators of higher carbohydrate and saturate fat craving. Lorcaserin, antiepileptic drugs, opioid antagonists, and antiaddictive agents may be intuitively used in food addiction, but clinical trials are necessary to confirm their efficacy.
- Country
- Country not stated
- Design
- Meta-analysis
- Licence
- CC BY
Effectiveness of Interventions for Prevention of Common Infections Among Opioid Users: A Systematic Review of Systematic Reviews
Puzhko et al. · 2022 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Meta-analysis
- Licence
- CC BY
Associations of employment status with opioid misuse: Evidence from a nationally representative survey in the U.S.
Matthews et al. · 2022 · United States
(Korean)
- Country
- United States
- Sample
- n = 40,143
- Design
- Cross-sectional
- Licence
- Other
(Korean title)
(Korean authors) · 2022 · United States
(Korean)
- Country
- United States
- Design
- Other
- Licence
- Other
The Kappa Opioid Receptor: A Promising Therapeutic Target for Multiple Pathologies
Dalefield et al. · 2022 · Country not stated
KOR agonists are potential alternatives to MOR agonists for pain due to anti-nociceptive effects, lack of abuse potential, and reduced respiratory depressive effects. Clinical use of KOR agonists is limited by adverse effects such as dysphoria, aversion, and sedation. G-protein biased KOR agonists may improve therapeutic index by avoiding β-arrestin-2-mediated dysphoric effects. Mixed opioid agonists like MP1104 produce anti-nociceptive effects without respiratory depression, conditioned place preference, or aversion in rodents. Peripherally restricted KOR agonists are being developed to reduce CNS-mediated side effects.
- Country
- Country not stated
- Design
- Meta-analysis
- Licence
- CC BY
Opioids and Falls Risk in Older Adults: A Narrative Review
Virnes et al. · 2022 · Netherlands
(Korean)
- Country
- Netherlands
- Design
- Other
- Licence
- CC BY-NC
Relative effectiveness of medications for opioid-related disorders: A systematic review and network meta-analysis of randomized controlled trials
Lim et al. · 2022 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Meta-analysis
- Licence
- CC BY
(Korean title)
(Korean authors) · 2021 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 1,873
- Design
- Cross-sectional
- Licence
- Other
Initiating buprenorphine to treat opioid use disorder without prerequisite withdrawal: a systematic review
Adams et al. · 2021 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 24
- Design
- Meta-analysis
- Licence
- CC BY
Illicitly Manufactured Fentanyl Entering the United States
Pergolizzi et al. · 2021 · United States
(Korean)
- Country
- United States
- Design
- Other
- Licence
- CC BY
Meeting the Needs of Families Involved in the Child Welfare System for Parental Substance Abuse: Outcomes From an Effectiveness Trial of the Families Actively Improving Relationships Program
Saldana et al. · 2021 · United States
(Korean)
- Country
- United States
- Sample
- n = 99
- Design
- Other
- Licence
- CC BY
Can touch this: training to correct police officer beliefs about overdose from incidental contact with fentanyl
Pozo et al. · 2021 · United States
(Korean)
- Country
- United States
- Sample
- n = 204
- Design
- Other
- Licence
- CC BY
Transcutaneous Auricular Neurostimulation (tAN): A Novel Adjuvant Treatment in Neonatal Opioid Withdrawal Syndrome
Jenkins et al. · 2021 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 8
- Design
- Other
- Licence
- CC BY
Cannabis and tobacco use prior to pregnancy and subsequent offspring birth outcomes: a 20-year intergenerational prospective cohort study
Hines et al. · 2021 · Australia
Also covers · Tobacco
(Korean)
- Country
- Australia
- Sample
- n = 665
- Design
- Other
- Licence
- CC BY
Opioid use disorder in pregnancy: leveraging provider perceptions to inform comprehensive treatment
Titus-Glover et al. · 2021 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 12
- Design
- Qualitative
- Licence
- CC BY
The elephant in the room; a qualitative study of perinatal fears in opioid use disorder treatment in Southern Appalachia
Leiner et al. · 2021 · United States
(Korean)
- Country
- United States
- Sample
- n = 27
- Design
- Qualitative
- Licence
- CC BY
PRimary Care Opioid Use Disorders treatment (PROUD) trial protocol: a pragmatic, cluster-randomized implementation trial in primary care for opioid use disorder treatment
Campbell et al. · 2021 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 170,000
- Design
- Other
- Licence
- CC BY
The Vicious Cycle: Problematic Family Relations, Substance Abuse, and Crime in Adolescence: A Narrative Review
Saladino et al. · 2021 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 61
- Design
- Meta-analysis
- Licence
- CC BY
Effects of Psychopathy on Neurocognitive Domains of Impulsivity in Abstinent Opiate and Stimulant Users
Psederska et al. · 2021 · Bulgaria
(Korean)
- Country
- Bulgaria
- Sample
- n = 693
- Design
- Cross-sectional
- Licence
- CC BY
Patient Satisfaction With Medications for Opioid Use Disorder Treatment via Telemedicine: Brief Literature Review and Development of a New Assessment
Cole et al. · 2021 · United States
(Korean)
- Country
- United States
- Sample
- n = 14
- Design
- Cross-sectional
- Licence
- CC BY
The Role of Trauma in Early Onset Borderline Personality Disorder: A Biopsychosocial Perspective
Bozzatello et al. · 2021 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 766
- Design
- Meta-analysis
- Licence
- CC BY
Cell-Type-Specific Adaptions in Striatal Medium-Sized Spiny Neurons and Their Roles in Behavioral Responses to Drugs of Abuse
Allichon et al. · 2021 · Country not stated
D1R-MSN and D2R-MSN form two largely segregated populations of striatal medium-sized spiny neurons expressing DA-D1 or DA-D2 receptors, respectively. About 5–15% of NAc MSN express both dopamine receptor subtypes depending on NAc subregions. Roughly half of NAc D1R-MSN has been shown to project in the ventral pallidum, the canonical output structure of indirect pathway MSN. Ablation, blockade, optogenetic inhibition or chemogenetic silencing of D1R-MSN tends to dampen behavioral adaptations to psychostimulants, while activation enhances these responses. Ablation or chemogenetic inhibition of D2R-MSN tends to enhance psychostimulant-evoked adaptations, while activation has opposite effects.
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
Molecular mechanisms of opioid tolerance: From opioid receptors to inflammatory mediators (Review)
Zhou et al. · 2021 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Other
- Licence
- Quote only
Alexithymia in Patients With Substance Use Disorders and Its Relationship With Psychiatric Comorbidities and Health-Related Quality of Life
Palma-Álvarez et al. · 2021 · Spain
(Korean)
- Country
- Spain
- Sample
- n = 126
- Design
- Cross-sectional
- Licence
- CC BY
Public support for harm reduction: A population survey of Canadian adults
Wild et al. · 2021 · Canada
(Korean)
- Country
- Canada
- Sample
- n = 4,645
- Design
- Cross-sectional
- Licence
- CC BY
Interaction of opioids with TLR4—mechanisms and ramifications
Gabr et al. · 2021 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
Opioids and Chronic Pain: An Analytic Review of the Clinical Evidence
Nadeau et al. · 2021 · United States
Estimated risk of death from opioid treatment involving doses above 100 MMED is approximately 0.25%/year. Prevalence of opioid use disorder associated with prescription opioids is likely less than 3%. Multiple large studies refute the concept that short-term opioid use for acute pain predisposes to opioid use disorder. In an EERW trial, 76.8% of completers achieved ≥30% pain reduction and 67.4% experienced >50% decrease in pain. Among participants, 53% were titrated to ≤90 MMED, 81% to ≤150 MMED, and 93% to ≤240 MMED.
- Country
- United States
- Sample
- n = 205
- Design
- Meta-analysis
- Licence
- CC BY
Changes in opioid mortality following increased access to opioid substitution treatment
Andersson et al. · 2020 · Sweden
(Korean)
- Country
- Sweden
- Design
- Other
- Licence
- CC BY
(Korean title)
(Korean authors) · 2020 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 6,932,776
- Design
- Other
- Licence
- Other
Community Care in Reach: Mobilizing Harm Reduction and Addiction Treatment Services for Vulnerable Populations
Regis et al. · 2020 · United States
(Korean)
- Country
- United States
- Sample
- n = 119
- Design
- Other
- Licence
- CC BY
Female mice are more prone to develop an addictive-like phenotype for sugar consumption
Wei et al. · 2020 · Germany
(Korean)
- Country
- Germany
- Sample
- n = 83
- Design
- Other
- Licence
- CC BY
“They look at us like junkies”: influences of drug use stigma on the healthcare engagement of people who inject drugs in New York City
Muncan et al. · 2020 · United States
(Korean)
- Country
- United States
- Sample
- n = 32
- Design
- Qualitative
- Licence
- CC BY
Training to reduce emergency responders' perceived overdose risk from contact with fentanyl: early evidence of success
Winograd et al. · 2020 · United States
(Korean)
- Country
- United States
- Sample
- n = 140
- Design
- Other
- Licence
- CC BY
In their own words: a qualitative study of factors promoting resilience and recovery among postpartum women with opioid use disorders
Goodman et al. · 2020 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 10
- Design
- Qualitative
- Licence
- CC BY
Crosstalk Between Kappa Opioid and Dopamine Systems in Compulsive Behaviors
Escobar et al. · 2020 · Country not stated
Acute activation of KOR decreases synaptic dopamine levels in the striatum, an effect shown by cerebral microdialysis in 1988. Direct infusion of the KOR antagonist nor-BNI increases basal dopamine levels in the NAc and dopamine release in the dorsal striatum. KOR knockout mice display increased extracellular dopamine levels in the striatum and NAc. Repeated KOR activation facilitates locomotor sensitization and compulsive checking behavior induced by repeated quinpirole administration. KOR blockade reverts dopaminergic changes in the dorsolateral striatum of amphetamine-sensitized rats without modifying their enhanced locomotor response to the drug.
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
Regulator of G-Protein Signaling (RGS) Protein Modulation of Opioid Receptor Signaling as a Potential Target for Pain Management
Senese et al. · 2020 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
Experiences of people taking opioid medication for chronic non-malignant pain: a qualitative evidence synthesis using meta-ethnography
Nichols et al. · 2020 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 31
- Design
- Meta-analysis
- Licence
- CC BY
Mu Opioid Receptor Heterodimers Emerge as Novel Therapeutic Targets: Recent Progress and Future Perspective
Zhang et al. · 2020 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
Dark Times: The Role of Negative Reinforcement in Methamphetamine Addiction
May et al. · 2020 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 400
- Design
- Meta-analysis
- Licence
- CC BY
Opioids in Post-stroke Pain: A Systematic Review and Meta-Analysis
Scuteri et al. · 2020 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Meta-analysis
- Licence
- CC BY
Pharmacological Treatment of Methamphetamine/Amphetamine Dependence: A Systematic Review
Siefried et al. · 2020 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 4,065
- Design
- Meta-analysis
- Licence
- Quote only
Escalated Oxycodone Self-Administration and Punishment: Differential Expression of Opioid Receptors and Immediate Early Genes in the Rat Dorsal Striatum and Prefrontal Cortex
Blackwood et al. · 2020 · Country not stated
Footshocks separated oxycodone self-administering rats into shock-sensitive (n = 5) and shock-resistant (n = 6) phenotypes. Mu and Kappa opioid receptor proteins decreased significantly only in the dorsal striatum of all oxycodone self-administration rats. Delta opioid receptor protein was decreased in both the dorsal striatum and prefrontal cortex. c-fos, fosB, fra2, junB, egr1, and egr2 mRNAs decreased significantly in the dorsal striatum (but not PFC) of shock-sensitive rats. egr3 mRNA expression was increased in the PFC of only shock-resistant rats.
- Country
- Country not stated
- Sample
- n = 28
- Design
- Other
- Licence
- CC BY
Retention of patients in opioid substitution treatment: A systematic review
O'Connor et al. · 2020 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 294,592
- Design
- Meta-analysis
- Licence
- CC BY
The Bell Tolls for Thee & Thine: Compassion Fatigue & the Overdose Epidemic
Winstanley · 2020 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Other
- Licence
- Other
A mixed-method comparison of physician-reported beliefs about and barriers to treatment with medications for opioid use disorder
Haffajee et al. · 2020 · United States
(Korean)
- Country
- United States
- Sample
- n = 151
- Design
- Other
- Licence
- CC BY
Financial incentives promote engagement in employment services for unemployed adults in treatment for opioid use disorder
Holtyn et al. · 2020 · United States
(Korean)
- Country
- United States
- Sample
- n = 91
- Design
- Other
- Licence
- Other
(Korean title)
(Korean authors) · 2020 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 9
- Design
- Qualitative
- Licence
- Other
Sex Differences and the Role of Estradiol in Mesolimbic Reward Circuits and Vulnerability to Cocaine and Opiate Addiction
Kokane et al. · 2020 · United States
(Korean)
- Country
- United States
- Design
- Meta-analysis
- Licence
- CC BY
(Korean title)
(Korean authors) · 2019 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 5
- Design
- Qualitative
- Licence
- Other
Predisposing and protective factors influencing suicide ideation, attempt, and death in patients accessing substance use treatment: a systematic review and meta-analysis protocol
Espinet et al. · 2019 · United States
(Korean)
- Country
- United States
- Sample
- n = 34,251
- Design
- Meta-analysis
- Licence
- CC BY
Advancing the implementation and sustainment of medication assisted treatment for opioid use disorders in prisons and jails
Ferguson et al. · 2019 · United States
Monthly OUD prevalence in participating facilities ranged from 28 to 65% of the population. The proportion of individuals with OUD who received MAT ranged considerably from 9 to 61%. Only one site achieved sustained growth in the proportion of individuals treated over the course of the project. Facilitators included increased staffing and staff training, group education, data-driven change, justice coordination, and post-release contact. Barriers included lack of funding, space and institutional design, cultural perceptions of treatments, and inability to sustain care coordination at release.
- Country
- United States
- Sample
- n = 4
- Design
- Other
- Licence
- CC BY
A Call for Consensus in Defining Efficacy in Clinical Trials for Opioid Addiction: Combined Results from a Systematic Review and Qualitative Study in Patients Receiving Pharmacological Assisted Therapy for Opioid Use Disorder
Dennis et al. · 2019 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 18
- Design
- Other
- Licence
- CC BY
Low barrier buprenorphine treatment for persons experiencing homelessness and injecting heroin in San Francisco
Carter et al. · 2019 · United States
(Korean)
- Country
- United States
- Sample
- n = 95
- Design
- Other
- Licence
- CC BY
Pain polymorphisms and opioids: An evidence based review
Vieira et al. · 2019 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Meta-analysis
- Licence
- Quote only
Chronic Pain and Chronic Opioid Use After Intensive Care Discharge – Is It Time to Change Practice?
Stamenkovic et al. · 2019 · United Kingdom
(Korean)
- Country
- United Kingdom
- Sample
- n = 575
- Design
- Meta-analysis
- Licence
- CC BY
rTMS Reduces Psychopathological Burden and Cocaine Consumption in Treatment-Seeking Subjects With Cocaine Use Disorder: An Open Label, Feasibility Study
Pettorruso et al. · 2019 · Italy
(Korean)
- Country
- Italy
- Sample
- n = 20
- Design
- Other
- Licence
- CC BY
Effects of Non-invasive Brain Stimulation on Stimulant Craving in Users of Cocaine, Amphetamine, or Methamphetamine: A Systematic Review and Meta-Analysis
Ma et al. · 2019 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 321
- Design
- Meta-analysis
- Licence
- CC BY
Molecular Imaging of Opioid and Dopamine Systems: Insights Into the Pharmacogenetics of Opioid Use Disorders
Burns et al. · 2019 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Meta-analysis
- Licence
- CC BY
Brain and Cognition for Addiction Medicine: From Prevention to Recovery Neural Substrates for Treatment of Psychostimulant-Induced Cognitive Deficits
D'Souza · 2019 · Country not stated
Also covers · Tobacco
Psychostimulant drugs induce cognitive deficits including impulsivity, poor decision making, impaired cognitive flexibility, and deficits in learning and memory. These drug-induced cognitive deficits often impact adherence to addiction treatment programs and predispose abstinent addicts to drug use relapse. Psychostimulant addicts show high levels of both behavioral and decisional impulsivity than do healthy controls. In animals, repeated administration of cocaine, methamphetamine, and nicotine increased impulsive behavior. Recovering addicts with significant cognitive deficits are more vulnerable to relapse.
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
Slow release oral morphine versus methadone for the treatment of opioid use disorder
Klimas et al. · 2019 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 471
- Design
- Meta-analysis
- Licence
- CC BY-NC
A Survey of Molecular Imaging of Opioid Receptors
Cumming et al. · 2019 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
The search for the "next" euphoric non-fentanil novel synthetic opioids on the illicit drugs market: current status and horizon scanning
Sharma et al. · 2019 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
Opioid Epidemic in the United States: Empirical Trends, and A Literature Review of Social Determinants and Epidemiological, Pain Management, and Treatment Patterns
Singh et al. · 2019 · United States
(Korean)
- Country
- United States
- Design
- Other
- Licence
- Quote only
Take-Home Naloxone for the Emergency Interim Management of Opioid Overdose: The Public Health Application of an Emergency Medicine
Strang et al. · 2019 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Other
- Licence
- Quote only
Pain Therapy Guided by Purpose and Perspective in Light of the Opioid Epidemic
Severino et al. · 2018 · United States
(Korean)
- Country
- United States
- Design
- Other
- Licence
- CC BY
Employment services and substance abuse treatment
Sherba et al. · 2018 · United States
(Korean)
- Country
- United States
- Sample
- n = 800
- Design
- Other
- Licence
- Other
Interaction Between Stress and Addiction: Contributions From Latin-American Neuroscience
Torres-Berrio et al. · 2018 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
National trends and characteristics of inpatient detoxification for drug use disorders in the United States
Zhu et al. · 2018 · United States
(Korean)
- Country
- United States
- Sample
- n = 271,403
- Design
- Cross-sectional
- Licence
- CC BY
The hot 'n' cold of cue-induced drug relapse
Pitchers et al. · 2018 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Cross-sectional
- Licence
- CC BY-NC
TAAR1 in Addiction: Looking Beyond the Tip of the Iceberg
Liu et al. · 2018 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
Opiate Drugs with Abuse Liability Hijack the Endogenous Opioid System to Disrupt Neuronal and Glial Maturation in the Central Nervous System
Hauser et al. · 2018 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
The Association of Unfavorable Traffic Events and Cannabis Usage: A Meta-Analysis
Hostiuc et al. · 2018 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Meta-analysis
- Licence
- CC BY
Vitamin B12 Levels in Methamphetamine Addicts
Zhai et al. · 2018 · China
Also covers · Tobacco
(Korean)
- Country
- China
- Sample
- n = 231
- Design
- Cross-sectional
- Licence
- CC BY
Lack of Effects of Extended Sessions of Transcranial Direct Current Stimulation (tDCS) Over Dorsolateral Prefrontal Cortex on Craving and Relapses in Crack-Cocaine Users
Klauss et al. · 2018 · Brazil
(Korean)
- Country
- Brazil
- Sample
- n = 35
- Design
- Other
- Licence
- CC BY
GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia liability
Pasman et al. · 2018 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 184,765
- Design
- Cross-sectional
- Licence
- Other
Heteromerization Modulates mu Opioid Receptor Functional Properties in vivo
Ugur et al. · 2018 · Country not stated
Native mu receptor heteromers were evidenced for delta, kappa, ORL1, CB1, Gal1, α2a, sst2, D1, CCR5, V1b, GRPR, and NMDA, using co-IP, electron microscopy, PLA, or interfering peptides. Mu-delta heteromerization induces cross-allosteric modulation with positive cooperativity, and co-application of subthreshold mu and delta agonists increased GABAergic inhibition in the RVM. Heteromers with non-opioid receptors such as Gal1 negatively modulate mu receptor G protein dependent signaling, with galanin dampening mu receptor signaling. Chronic morphine treatment enhances mu-delta heteromer density in brain regions associated with the reward pathway, with a concomitant mu-dependent increase in delta receptor surface localization. Expression of mu-α2a heteromers in the NTS is dynamically regulated and increased in hypertensive rats.
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
Racial Bias in the US Opioid Epidemic: A Review of the History of Systemic Bias and Implications for Care
Santoro et al. · 2018 · United States
(Korean)
- Country
- United States
- Design
- Qualitative
- Licence
- CC BY
Advances in Achieving Opioid Analgesia Without Side Effects
Machelska et al. · 2018 · Country not stated
Opioid actions are mediated by µ-, δ-, and κ-opioid receptors, which are G protein-coupled receptors. µ-receptor activation causes respiratory depression, sedation, constipation, nausea, vomiting, reward/euphoria, and dependence/withdrawal. δ-receptor activation can cause convulsions and may produce reward; κ-receptor agonists exert aversion/dysphoria, sedation, and diuresis. Peripheral opioid receptors mediate effective analgesia but are not involved in fatal effects in animal models and humans. β-arrestin-2 might be involved in morphine-induced analgesic tolerance, respiratory depression, and constipation.
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
Psychiatric Co-Morbidities in Pregnant Women with Opioid Use Disorders: Prevalence, Impact, and Implications for Treatment
Arnaudo et al. · 2017 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 531
- Design
- Meta-analysis
- Licence
- CC BY
Opioid-Induced Constipation and Bowel Dysfunction: A Clinical Guideline
Müller-Lissner et al. · 2017 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 33
- Design
- Meta-analysis
- Licence
- Quote only
Review about gabapentin misuse, interactions, contraindications and side effects
Quintero · 2017 · United Kingdom
(Korean)
- Country
- United Kingdom
- Sample
- n = 1,500
- Design
- Meta-analysis
- Licence
- CC BY-NC
Mortality risk during and after opioid substitution treatment: systematic review and meta-analysis of cohort studies
Sordo et al. · 2017 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 122,885
- Design
- Meta-analysis
- Licence
- Other
Co-occurring Attention Deficit Hyperactivity Disorder symptoms in adults affected by heroin dependence: Patients characteristics and treatment needs
Lugoboni et al. · 2017 · Italy
Also covers · Tobacco
(Korean)
- Country
- Italy
- Sample
- n = 1,057
- Design
- Cross-sectional
- Licence
- Other
Cannabis use, COMT, BDNF and age at first-episode psychosis
Mané et al. · 2017 · Spain
(Korean)
- Country
- Spain
- Sample
- n = 260
- Design
- Cross-sectional
- Licence
- Other
‘Spending My Own Money, Harming My Own Body’: Addiction Care in a Chinese Therapeutic Community
Hyde · 2017 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Qualitative
- Licence
- Other
Primary care models for treating opioid use disorders: What actually works? A systematic review
Lagisetty et al. · 2017 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 35
- Design
- Meta-analysis
- Licence
- Quote only
Is there room for resilience? A scoping review and critique of substance use literature and its utilization of the concept of resilience
Rudzinski et al. · 2017 · Country not stated
A total of 396 studies were retrieved; 319 were excluded and 77 were selected for providing a definition or operationalization of resilience. The majority of studies focus on youth and their resistance to, or engagement in, substance use. A small but growing area of research examines recovery from substance addiction as a form of resilience. Drug use is consistently presented as a 'risk factor' or 'maladaptive coping strategy' in the literature. Current conceptualizations of resilience are too narrow to recognize all potential manifestations of resilience practices in the daily lives of individuals who actively use drugs.
- Country
- Country not stated
- Sample
- n = 77
- Design
- Meta-analysis
- Licence
- CC BY
Access to substance use treatment among young adults who use prescription opioids non-medically
Liebling et al. · 2016 · United States
(Korean)
- Country
- United States
- Sample
- n = 200
- Design
- Cross-sectional
- Licence
- CC BY
MicroRNAs Modulate Interactions between Stress and Risk for Cocaine Addiction
Doura et al. · 2016 · Country not stated
Mice deficient in Ago2 in Drd2-expressing striatal neurons self-administer fewer cocaine infusions with a downward shift in the dose-response curve. Ago2-deficient mice show no preference for cocaine paired environments in conditioned place preference, unlike wild-type controls. Overexpression of miR-181a in the nucleus accumbens increases cocaine-induced conditioned place preference, whereas knockdown has the opposite effect. Overexpression of miR-124 in the nucleus accumbens attenuates cocaine conditioned place preference. miR-212 is upregulated 1.75-fold in dorsal striatum of rats with extended cocaine access; overexpression lowers cocaine self-administration.
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
Opioid Prescribing After Nonfatal Overdose and Association With Repeated Overdose: A Cohort Study
Larochelle et al. · 2016 · United States
(Korean)
- Country
- United States
- Sample
- n = 2,848
- Design
- Other
- Licence
- Other
Neuroimmune Interaction in the Regulation of Peripheral Opioid-Mediated Analgesia in Inflammation
Hua · 2016 · Country not stated
Opioid receptors on peripheral sensory nerve terminals are activated by endogenous opioid peptides from immune cells, producing significant analgesia without central side effects. In early inflammation granulocytes (esp. neutrophils) are the major opioid-containing leukocyte; at later stages monocytes/macrophages and lymphocytes predominate. Inflammation increases opioid peptide expression and precursor mRNA in immune cells, with β-endorphin from pro-opiomelanocortin being the most prominent. Inflamed tissue shows increased metabolic breakdown of opioid peptides, suggesting release must occur close to peripheral opioid receptors. Opioid release from immune cells is calcium dependent, consistent with a regulated secretory vesicle pathway.
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
Pharmacotherapy of Pain in the Older Population: The Place of Opioids
Prostran et al. · 2016 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
Opioids and Viral Infections: A Double-Edged Sword
Tahamtan et al. · 2016 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
Opioid Drugs in Patients With Liver Disease: A Systematic Review
Soleimanpour et al. · 2016 · Country not stated
In patients with liver disease, opioid analgesics should be administered cautiously, with lower doses at regular intervals based on signs of drug accumulation. Interactions of opioid drugs with different levels of substrates of the P450 cytochrome enzyme should be considered. Opioids should be used cautiously since they can cause sedation, constipation and sudden encephalopathy effects. Since clearance of these drugs in patients with hepatic insufficiency is decreased, the initial dose must be decreased and intervals between doses increased.
- Country
- Country not stated
- Design
- Meta-analysis
- Licence
- CC BY
Long-term self-treatment with methadone or buprenorphine as a response to barriers to opioid substitution treatment: the case of Sweden
Richert et al. · 2015 · Sweden
(Korean)
- Country
- Sweden
- Sample
- n = 27
- Design
- Qualitative
- Licence
- CC BY
Methamphetamine and the hypothalamic-pituitary-adrenal axis
Zuloaga et al. · 2015 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
Role of the endogenous cannabinoid system in nicotine addiction: novel insights
Gamaleddin et al. · 2015 · Country not stated
Also covers · Tobacco
(Korean)
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
Disruption of gut homeostasis by opioids accelerates HIV disease progression
Meng et al. · 2015 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
Glutamatergic synaptic plasticity in the mesocorticolimbic system in addiction
Huijstee et al. · 2015 · Country not stated
Also covers · Tobacco
A single in vivo cocaine exposure significantly increased the AMPAR/NMDAR ratio in VTA DA neurons, reflecting enhanced AMPAR and decreased NMDAR transmission. All addictive drugs tested (morphine, nicotine, benzodiazepines, ethanol) potentiated AMPAR transmission in VTA DA neurons 24 h after a single dose, whereas fluoxetine and carbamazepine did not. Cocaine-induced potentiation was present within 3 h, still observed after 5 days, but not after 10 days. Enhanced AMPAR transmission results from insertion of GluA2-lacking AMPARs, and the increased ratio also involves a GluN2B-to-GluN2A switch and GluN3A-containing NMDARs. Cocaine-induced plasticity was absent in D5 receptor knockout mice and in GluN3A knockout mice.
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
Sex Differences in Kappa Opioid Receptor Function and Their Potential Impact on Addiction
Chartoff et al. · 2015 · Country not stated
Stress, anxiety, and depression are tightly linked to addiction, and whether they precede or result from compulsive drug use depends on many factors, including biological sex. KOR agonists produce signs of anxiety, fear, and depression in laboratory animals and humans, but these studies were almost exclusively conducted in males. Recent work from the authors' lab shows that female rats are less sensitive than males to the depressive-like effects of a KOR agonist (Russell et al., 2014). Drug-dependent women express greater negative emotional states such as stress and depression, and these are more likely to trigger craving and relapse in women than men. Women are twice as likely as men to suffer from anxiety and depression (Kessler, 2003).
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
The effects of adolescent methamphetamine exposure
Buck et al. · 2015 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
(Korean title)
(Korean authors) · 2015 · South Korea
Also covers · Smartphone
(Korean)
- Country
- South Korea
- Sample
- n = 7
- Design
- Qualitative
- Licence
- Other
Salvinorin A, a kappa-opioid receptor agonist hallucinogen: pharmacology and potential template for novel pharmacotherapeutic agents in neuropsychiatric disorders
Butelman et al. · 2015 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
Opioid-induced hyperalgesia in chronic pain patients and the mitigating effects of gabapentin
Stoicea et al. · 2015 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Meta-analysis
- Licence
- CC BY
Kir3 channel signaling complexes: focus on opioid receptor signaling
Nagi et al. · 2014 · Country not stated
Kir3.1/3.2 heterotetramers are considered prototypical neuronal channels, and Kir3 channel activation contributes to opioid analgesia in animal models. Mice with Kir3.2 insensitive to G protein activation showed reduced analgesic responses to morphine. Knock-out of Kir3.2 and 3.3 interfered with morphine's ability to prolong avoidance behavior in the hot plate test. Kir3.3 ablation was without effect on the analgesic response elicited by intrathecal morphine. Variations in KCNJ6 influence opioid dose requirements, while KCNJ3 variations showed no effect.
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
The kappa opioid receptor: from addiction to depression, and back
Lalanne et al. · 2014 · Country not stated
Systemic administration of the KOR agonist U69593 or morphine yielded opposite effects, respectively producing CPA and CPP. KOR-induced CPA was abolished in DAT KOR-cKO mice, and restored upon virally mediated KOR re-expression in the VTA. Infusion of the KOR agonist U50,488H in the NAc was sufficient to induce a robust CPA. DA release in the NAc was decreased by infusion of a KOR agonist into the NAc, but not into the VTA. Infusion of a KOR antagonist (nor-BNI) into the NAc increased DA release.
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
The Therapeutic Use of Analgesics in Patients With Liver Cirrhosis: A Literature Review and Evidence-Based Recommendations
Imani et al. · 2014 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Meta-analysis
- Licence
- CC BY-NC
Intraoperative use of remifentanil and opioid induced hyperalgesia/acute opioid tolerance: systematic review
Kim et al. · 2014 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Meta-analysis
- Licence
- CC BY
Impact of ABCB1 and CYP2B6 Genetic Polymorphisms on Methadone Metabolism, Dose and Treatment Response in Patients with Opioid Addiction: A Systematic Review and Meta-Analysis
Dennis et al. · 2014 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Meta-analysis
- Licence
- CC BY
(Korean title)
(Korean authors) · 2014 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 454
- Design
- Other
- Licence
- Other
Kronic hysteria: Exploring the intersection between Australian synthetic cannabis legislation, the media, and drug-related harm
Bright et al. · 2013 · Australia
(Korean)
- Country
- Australia
- Design
- Other
- Licence
- Quote only
Executive cognitive dysfunction and ADHD in cocaine dependence: searching for a common cognitive endophenotype for addictive disorders
Cunha et al. · 2013 · Brazil
(Korean)
- Country
- Brazil
- Sample
- n = 101
- Design
- Cross-sectional
- Licence
- CC BY
Positive youth development, life satisfaction, and problem behaviors of adolescents in intact and non-intact families in Hong Kong
Shek et al. · 2013 · Hong Kong SAR China
Also covers · Smartphone
(Korean)
- Country
- Hong Kong SAR China
- Sample
- n = 3,328
- Design
- Cross-sectional
- Licence
- CC BY
Structural and Functional Imaging Studies in Chronic Cannabis Users: A Systematic Review of Adolescent and Adult Findings
Batalla et al. · 2013 · Country not stated
142 studies were identified, of which 43 met the established criteria; 8 studies were in adolescent population. Morphological brain alterations were found in both adolescents and adults, particularly in medial temporal and frontal cortices, as well as the cerebellum. These structural effects may be related to the amount of cannabis exposure. Functional neuroimaging studies suggest different patterns of resting global and brain activity during several cognitive tasks in both adolescents and adults. These functional differences may indicate compensatory effects in response to chronic cannabis exposure.
- Country
- Country not stated
- Design
- Meta-analysis
- Licence
- CC BY
Let-7 microRNAs and opioid tolerance
He et al. · 2012 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY-NC
Morphine and microRNA activity: is there a relation with addiction?
Rodríguez · 2012 · Country not stated
miR-let-7 acts as a mediator of the movement of the mu opioid receptor (MOR) mRNA into P-bodies, leading to translational repression. miR-23b links MOR expression and morphine treatment at the post-transcriptional level; long-term morphine treatment increases miR-23b expression in a dose- and time-dependent manner. Fentanyl increases NeuroD levels by reducing the amount of miR-190, but morphine does not affect the levels of NeuroD. Morphine treatment of monocytes led to a decrease in several anti-HIV miRNAs (mir-28, 125b, 150, and 382). Morphine modulates the expression of miR-133b and of its target transcript Pitx3, and morphine-induced regulation of miR-133b depends on ERK1/2 via zfMOR.
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
(Korean title)
(Korean authors) · 2011 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 447
- Design
- Cross-sectional
- Licence
- Other
Risky decision-making predicts short-term outcome of community but not residential treatment for opiate addiction. Implications for case management
Passetti et al. · 2011 · United Kingdom
(Korean)
- Country
- United Kingdom
- Sample
- n = 80
- Design
- Other
- Licence
- Other
Anorexia Nervosa: A Unified Neurological Perspective
Hasan et al. · 2011 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY-NC
What can we learn from the Portuguese decriminalization of illicit drugs?
Hughes et al. · 2010 · Portugal
(Korean)
- Country
- Portugal
- Sample
- n = 13
- Design
- Other
- Licence
- Other
Cocaine- and Amphetamine-Regulated Transcript (CART) Signaling within the Paraventricular Thalamus Modulates Cocaine-Seeking Behaviour
James et al. · 2010 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
Illicit drug use and problematic use in the elderly: is there a case for concern?
Shah et al. · 2008 · United States
(Korean)
- Country
- United States
- Design
- Other
- Licence
- Quote only
Ethanol/Naltrexone Interactions at the mu-Opioid Receptor. CLSM/FCS Study in Live Cells
Vukojević et al. · 2008 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Other
- Licence
- CC BY
Methadone and buprenorphine for the management of opioid dependence: a systematic review and economic evaluation
Connock et al. · 2007 · United Kingdom
(Korean)
- Country
- United Kingdom
- Design
- Meta-analysis
- Licence
- Quote only
The mental health risks of adolescent cannabis use
Hall · 2006 · Sweden
(Korean)
- Country
- Sweden
- Sample
- n = 50,465
- Design
- Other
- Licence
- CC BY
Potential community and public health impacts of medically supervised safer smoking facilities for crack cocaine users
Shannon et al. · 2006 · Canada
Also covers · Tobacco
Recent injection drug use was independently associated with willingness to use a SSF (OR = 1.72, 95% CI: 1.09–2.70). Having equipment confiscated or broken by police was associated with willingness to use a SSF (OR = 1.96, 95% CI: 1.24–2.85). Crack bingeing (OR = 2.16, 95% CI: 1.39–3.12) and smoking crack in public places (OR = 2.48, 95% CI: 1.65–3.27) were associated with willingness. Borrowing crack pipes (OR = 2.50, 95% CI: 1.86–3.40) and burns/inhaled brillo due to rushing smoke in public places (OR = 4.37, 95% CI: 2.71–8.64) were associated with willingness.
- Country
- Canada
- Sample
- n = 437
- Design
- Cross-sectional
- Licence
- CC BY
(Korean title)
Lyoo et al. · 2005 · South Korea
(Korean)
- Country
- South Korea
- Sample
- n = 49
- Design
- Cross-sectional
- Licence
- Other
Efficacy of acupuncture for cocaine dependence: a systematic review & meta-analysis
Mills et al. · 2005 · United States
(Korean)
- Country
- United States
- Sample
- n = 1,747
- Design
- Meta-analysis
- Licence
- CC BY
Effectiveness of Substance Abuse Treatment Programming for Women: A Review
Ashley et al. · 2003 · Country not stated
(Korean)
- Country
- Country not stated
- Sample
- n = 38
- Design
- Meta-analysis
- Licence
- Other
Screening for hepatitis C among injecting drug users and in genitourinary medicine clinics: systematic reviews of effectiveness, modelling study and national survey of current practice
Stein et al. · 2002 · Country not stated
(Korean)
- Country
- Country not stated
- Design
- Other
- Licence
- Quote only